Retroperitoneal sarcomas (RPS), a rare subset of soft tissue sarcomas, account for 10-15% of these cases and are distinguished by their substantial size, infiltrative nature, and proximity to vital anatomical structures.

Some patients with soft tissue sarcomas may be inoperable due to medical comorbidity or might decline radical or amputative surgeries due to undesirable functional outcomes.

In contradistinction to many other malignancies, gynecologic cancers continue to rise in incidence and/or mortality. By 2030, endometrial cancer will be one of the top three female cancers, exceeding colon cancer rates.

Each year in the U.S., thousands of pregnant people will be diagnosed with cancer and face the need for radiotherapy.

Management of unknown primary head and neck squamous cell carcinomas has evolved as the incidence of p16 positive disease among head and neck cancer patients has increased.

In medical imaging and radiation oncology, image synthesis refers to generating a target image modality from a given source modality, for example, synthetic CT images from MRI simulations for treatment planning.

Metastasis is the final common lethal pathway for most cancer patient's demise and once cancer has metastasized, it was generally considered incurable.

The use of radiotherapy (RT) in the management of leukemia has evolved. Historically, RT was critical for disease control in sanctuary sites, such as the central nervous system (CNS) and testes.

Liquid biopsy technologies, particularly circulating tumor DNA (ctDNA), are an emerging tool in precision oncology with growing relevance in radiation oncology.