Partial breast irradiation (PBI) has emerged as an increasingly important treatment option for appropriately selected patients with early-stage breast cancer, offering a more targeted approach to radiation therapy while reducing treatment burden and minimizing exposure to surrounding normal tissu

An estimated 90% of patients treated with radiotherapy for breast cancer will develop radiation-induced dermatitis. On the molecular level, radiation upregulates cytokine cascades and fibro-inflammatory pathways, leading to substantial fibrosis, the hallmark of chronic RT damage.

As complexity of radiation therapy increases, ensuring that health care institutions meet rigorous quality standards becomes paramount.

The role of radiotherapy in the management of benign diseases is ever expanding. Non-malignant entities of the head and neck are particularly complex and represent therapeutic challenges given the potential for treatment-associated morbidities.

The management of patients with nasal cavity and paranasal sinus tumors is challenging and constantly evolving. It often requires true trimodality care involving radiation oncology, otolaryngology and medical oncology, along with a variety of different supportive services.