This session will review the recent literature on radiation for upper and lower GI cancers. Specific cancers that will be addressed are esophageal cancer, gastric cancer, pancreatic cancer, and biliary tract cancer. Trials that utilize radiotherapy will be discussed. The audience will know when the appropriate clinical scenarios that radiation may offer benefit and those scenarios where radiotherapy may not be appropriate.

The treatment paradigms for the management of rectal cancers continues to evolve with more data emerging on short course radiotherapy, total neoadjuvant therapy, and the development of non-operative management algorithms. Given the rapid evolution an understanding of the available data is crucial to the practitioner to provide high quality and cost-effective care to patients. For anal cancers, a malignancy treated definitively with chemoradiation, advances in radiotherapy techniques has reduced significant toxicity in this patient cohort. An in depth understanding of radiotherapy simulation, treatment planning and treatment delivery for anorectal cancers will be provided that can be immediately incorporated into clinical practice.