This activity includes a panel of experts from breast radiation oncology, surgical oncology, medical oncology, and pathology to discuss the following rare histologies/breast cancer presentations: 1) Pleomorphic LCIS- diagnosis and differential (path) appropriate margin width (surgeon), role of adjuvant radiation (rad onc), role for endocrine therapy (med onc) 2) Phyllodes tumor- diagnosis and differential (path), surgical management (surg onc), adjuvant RT (rad onc) - discuss NRG trial on Phyllodes as part of the panel 3) Male breast cancer- mastectomy vs. breast conservation (surgery), use of genomic scores like oncotype, tamoxifen vs. AI, (med onc), role of adjuvant radiation and how it differs from women (rad onc) 4. Metaplastic breast cancer: mastectomy vs. breast conservation and optimal margin width (surg onc), systemic therapy, endocrine therapy and more targeted agents (med onc), adjuvant RT (rad onc). 

Topics:

1. Welcome and Introduction to the Panel; Case 1 Presentation
   Naamit Kurshan Gerber, MD - Introduction
   Jorge Reis-Filho, MD, PhD - Case 1 presentation
   Kandace P. McGuire, MD - Summary and discussion of Case 1
   Jose Pablo Leone, MD - Closing comments on Case 1
2. Case 2
   Naamit Kurshan Gerber, MD - Introduction of Case 2
   Jorge Reis-Filho, MD, PhD - Case 2 presentation
   Kandace P. McGuire, MD and Wendy A. Woodward, MD, PhD, FASTRO - Summary, Discussion and Q&A for Case 2
3. Case 3 - Phyllodes Tumors
   Naamit Kurshan Gerber, MD - Introduction of Case 3
   Kandace P. McGuire, MD and Kiri Cook, MD - Case 3 presentation
   Jose Pablo Leone, MD and Wendy A. Woodward, MD, PhD, FASTRO - Comments on Case 3
4. Case 4 - Male Breast Cancer
   Naamit Kurshan Gerber, MD - Introduction of Case 4
   Jose Pablo Leone, MD and Kiri Cook, MD - Case 4 presentation
   Full Panel - Discussion and Q&A for Case 4

This activity is available from September 12, 2023, through 11:59 p.m. Eastern time on September 11, 2025. 

This activity was originally recorded at the 2022 ASTRO Annual Meeting.