Skull-based cancers are complex and heterogeneous diseases that require complex multidisciplinary management between head and neck surgeons, medical oncologists and radiation oncologists. Emerging data has given novel insights into the optimal treatment of sinonasal and skull-based malignancies. Failure to keep up to date on emerging data and multidisciplinary considerations leads to worse patient outcomes.

It is critical that physicians that take care of patients with skull-based malignancies are knowledgeable about multidisciplinary considerations for the care of these patients. This session will provide the audience a case-based multidisciplinary discussion about optimal multimodality management of these complex diseases. This session will review novel and emerging approaches to skull-based malignancies in terms of role of systemic therapy, response adaptive surgery and novel radiation approaches. Physicians that take care of patients with sinonasal cancers require up to date case-based considerations that result in personalized treatment for patients that optimize survival while minimizing long-term treatment related toxicities.

Multimodality treatment is the cornerstone of skull-based and sinonasal malignancies of the head and neck. These diseases require domain-specific expertise with considerations for systemic therapy, radiation therapy and surgical approaches. Recent emerging data regarding neoadjuvant chemotherapy, organ preserving strategies, and response-adaptive treatment approaches have contributed to the body of evidence that drives optimal multidisciplinary treatment of these diseases. This activity uses a data-driven, case-based approach to discuss emerging data in the context of multimodality treatment of sinonasal and other skull-based malignancies of the head and neck.