Recent landmark studies in melanoma, cutaneous squamous cell carcinoma (cSCC), head and neck cancer (HNC) and sarcoma have established neoadjuvant immune therapy as a potential standard of care for patients with locally advanced cancers.

Radiation oncologists see patients across a wide spectrum of oncologic diseases and clinical conditions. Whether as a result of disease burden, cancer-directed treatment, or other unrelated problems, many patients present to radiation oncology clinic with significant symptom management needs.

Symptoms from cancer are often best palliated by multimodal therapies performed by different physicians.

This journal activity provides a summary of the current state of Early-Stage Breast Cancer radiotherapy treatments and an overview of the clinical data that can be used to create a more personalized radiotherapeutic management of patients based on molecular profiling and risk stratification.