Raising the Bar and Lowering Uncertainties in Reirradiation

With technological advances re-irradiation has rapidly become common and an important part of cancer management to new or recurrent tumors, yet is clinically challenging given risks of serious toxicity from cumulative doses. Institutional re-irradiation practices vary widely, though often involve a series of highly complex technical procedures coordinated by an interdisciplinary care team including across institutions. In the absence of evidence-based guidelines on re-irradiation best practices, an ESTRO-EORTC consensus paper has outlined technical aspects that must be accounted for in order to guide re-irradiation strategies. These include radiobiology and functional imaging to account for tissue recovery, and dosimetry aspects such as the using of deformable image registration to estimate cumulative doses in drastically different patient anatomy. Understanding the appropriateness and limitations of these processes is critical in their routine application in the clinic, and therefore re-irradiation necessitates interdisciplinary collaboration between oncologists, physicists, therapists and other team members. This activity facilitates more consistent, safe and high-quality care for patients receiving re-irradiation to manage their cancer.

Topics:

  1. Application of PRO's to Clinical Trials
    Deborah W. Bruner, PhD, RN, FAAN
  2.  

This activity is available from December 8, 2025, through 11:59 p.m. Eastern time on December 7, 2027. 

The content was originally presented and recorded at the 2025 ASTRO Annual Meeting.

Target Audience

The activity is designed to meet the interests of radiation oncologists, physicists, radiation therapists, dosimetrists and radiation biologists.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Implement routine clinical workflows for re-irradiation cases to communicate, document and account for all previous radiation treatments.
  • Determine optimal use of reirradiation dose summation methods, including deformable image registration.
  • Explain radiobiological considerations, including tissue recovery, and functional imaging studies that may be used to analyze function post treatment.
Course summary
Available credit: 
  • 1.25 AMA PRA Category 1 Credit™

    The American Society for Radiation Oncology (ASTRO) is accredited by the Accreditation Council for Continuing Medical Education for physicians. ASTRO designates this for a maximum of 1.25 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

  • 1.25 Certificate of Attendance
    This activity was designated for 1.25 AMA PRA Category 1 Credit™.
Course opens: 
12/08/2025
Course expires: 
12/07/2027
Cost:
$149.00
Rating: 
0
  • Erin F. Gillespie, MD, MPH, is employed by University of California, San Diego. Dr. Gillespie serves an uncompensated role as Co-founder of eContour.  
  •  

All relevant financial relationships have been mitigated.

The American Society for Radiation Oncology (ASTRO) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Available Credit

  • 1.25 AMA PRA Category 1 Credit™

    The American Society for Radiation Oncology (ASTRO) is accredited by the Accreditation Council for Continuing Medical Education for physicians. ASTRO designates this for a maximum of 1.25 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

  • 1.25 Certificate of Attendance
    This activity was designated for 1.25 AMA PRA Category 1 Credit™.

Price

Cost:
$149.00
Please login or register to take this course.

Course Fees:
ASTRO members must log in to the ASTRO website to view and receive the member rate.

  • Nonmember: $149
  • Member: $99
  • Member-in-Training: $49
  • Student/Graduate Student/PGY-1 Member: $49
  • Postdoctoral Fellow Member: $49

If you are an ASTRO member from a low or lower-middle income country, as identified by the World Bank, you can receive a 50% discount off your corresponding registration for this activity. Please email [email protected] to inquire about the discount.

Policies:
No refunds, extensions, or substitutions will be made for those participants who, for any reason, have not completed the activity by the expiration date. 

Participants using ASTRO Academy activities to satisfy the requirement of a Continuing Certification (MOC) program should verify the credit number and type and availability dates of any activity before making a purchase. No refunds, extensions, or substitutions will be made for participants who have purchased activities that do not align with their MOC requirement.

The activity and its materials will only be available on the ASTRO website until December 7, 2027, regardless of purchase date. At the expiration of the activity, participants will no longer have access to the activity or its materials. ASTRO reserves the right to remove an activity before its expiration date. 

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