RO Principles & Practice: Histology-Driven Management of Soft Tissue Sarcoma
This presentation is aimed at residents in advanced years of training and attending physicians seeking a practical update on the management of patients with soft tissue sarcoma. The focus is primarily on how histologic subtype shapes treatment paradigms with the goal of the talk is to bring radiation oncologists up to speed on the latest developments in these nuances in management. Using a mostly case-based approach, this teaching session reviews a variety of soft tissue sarcoma topics, including imaging assessment, treatment technique, CTV margins, dose of radiation, management of lymph nodes, use of chemotherapy, oligoprogression, and the importance of radiation in retroperitoneal sarcoma.
This presentation is part of the RO Principles & Practice project. RO Principles & Practice is an initiative of the ASTRO Education Committee aimed at building a peer-reviewed library of foundational lectures spanning the breadth of radiation oncology. Developed and delivered by exceptional educators in the field, this program will offer high-quality core content across major disease sites and clinical domains. Designed with senior residents and early-career radiation oncologists in mind, RO Principles & Practice supports the transition from training to practice with accessible educational resources from a trusted source.
This activity is available from June 17, 2026, through 11:59 p.m. Eastern time on June 16, 2028.
Target Audience
The activity is designed to meet the interests of radiation oncologists and residents.
Learning Objectives
Upon completion of this activity, participants should be able to:
- Describe specific patient and tumor factors that guide radiotherapy decisions regarding technique, dose, and timing for
soft tissue sarcoma. - Understand when the addition of systemic therapy may benefit patients with soft tissue sarcoma.
- Provide a rational for adding pre-operative radiotherapy in patients with retroperitoneal sarcoma.
Speaker:
- Ted Yanagihara, MD, PhD is employed by the University of North Carolina, Chapel Hill and has no relevant financial relationships to disclose.
Planners:
- Malcolm Mattes, MD, is employed by Rutgers Cancer Institute. Dr. Mattes has research funding from Gilead Sciences [ended 8/30/2025].
- Avinash Chaurasia, MD is employed by the U.S. Army and has no relevant financial relationships to disclose.
Reviewer:
- Michael Haddock, MD is employed by Mayo Clinic and has no relevant financial relationships to disclose.
All relevant financial relationships have been mitigated.
The American Society for Radiation Oncology (ASTRO) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Available Credit
- 1.25 AMA PRA Category 1 Credit™
The American Society for Radiation Oncology (ASTRO) is accredited by the Accreditation Council for Continuing Medical Education for physicians. ASTRO designates this Enduring material for a maximum of 1.25 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
- 1.25 Certificate of AttendanceThis activity was designated for 1.25 AMA PRA Category 1 Credit™.
Price
Course Fees:
ASTRO members must log in to the ASTRO website to view and receive the member rate.
- Nonmember: $149
- Member: $99
- Member-in-Training: $49
- Student/Graduate Student/PGY-1 Member: $49
- Postdoctoral Fellow Member: $49
If you are an ASTRO member from a low or lower-middle income country, as identified by the World Bank, you can receive a 50% discount off your corresponding registration for this activity. Please email [email protected] to inquire about the discount.
Policies:
No refunds, extensions, or substitutions will be made for those participants who, for any reason, have not completed the activity by the expiration date.
Participants using ASTRO Academy activities to satisfy the requirement of a Continuing Certification (MOC) program should verify the credit number and type and availability dates of any activity before making a purchase. No refunds, extensions, or substitutions will be made for participants who have purchased activities that do not align with their MOC requirement.
The activity and its materials will only be available on the ASTRO website until June 16, 2028, regardless of purchase date. At the expiration of the activity, participants will no longer have access to the activity or its materials. ASTRO reserves the right to remove an activity before its expiration date.
Required Hardware/software
One of the two latest versions of Google Chrome, Mozilla Firefox, Internet Explorer or Safari.

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