RO Principles & Practice: Adjuvant Radiotherapy After Laryngectomy

This educational activity focuses on the role of adjuvant therapy following total laryngectomy for laryngeal and hypopharyngeal cancers. We review evidence demonstrating improved locoregional control and survival in high-risk patients receiving postoperative radiotherapy or chemoradiotherapy, as well as the recent role of neoadjuvant therapy. Particular areas of focus include the optimal timing of treatment, incidence and management of acute and late toxicities, and voice and swallowing rehabilitation. A key theme of this activity is multidisciplinary collaboration.

This presentation is part of the RO Principles & Practice project. RO Principles & Practice is an initiative of the ASTRO Education Committee aimed at building a peer-reviewed library of foundational lectures spanning the breadth of radiation oncology. Developed and delivered by exceptional educators in the field, this program will offer high-quality core content across major disease sites and clinical domains. Designed with senior residents and early-career radiation oncologists in mind, RO Principles & Practice supports the transition from training to practice with accessible educational resources from a trusted source.

This activity is available from November 20, 2026, through 11:59 p.m. Eastern time on November 19, 2028. 

Jacob Miller, MD is an Assistant Professor in the Department of Radiation Oncology at Case Western Reserve University and a Member of the Cancer Genomics and Epigenomics Program at Case Comprehensive Cancer Center.

He is a radiation oncologist subspecializing in the treatment of head/neck neoplasms within Cleveland Clinic's Taussig Cancer Institute. As a translational research scientist, he also has a dual appointment within the Center for Immunotherapy and Precision Immuno-Oncology, wherein he conducts laboratory-based research studying virally-associated neoplasms of the oropharynx, nasopharynx, and anal canal. As a native of Ohio and alumnus of both Case Western Reserve University and the Lerner College of Medicine, Miller is passionate about the prevention and treatment of these cancers in his community. His research is focused on early detection, biomarker-adapted therapy, and immunotherapy resistance for these cancers using a molecular biology approach. He also has extensive experience in bioinformatics and epidemiologic microsimulations of tumor progression to aid the design of cancer screening programs. 

Target Audience

The activity is designed to meet the interests of radiation oncologists and residents.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Summarize the benefit and indications for adjuvant radiotherapy, adjuvant chemoradiotherapy, and integration of
    neoadjuvant immunotherapy.
  • Manage patients perioperatively with respect to voice and swallowing rehabilitation in collaboration with head/neck
    surgeons and speech-language pathologists.

Course summary

Available credit: 
  • 1.00 AMA PRA Category 1 Credit™

    The American Society for Radiation Oncology (ASTRO) is accredited by the Accreditation Council for Continuing Medical Education for physicians. ASTRO designates this for a maximum of 1.00 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

  • 1.00 Certificate of Attendance
    This activity was designated for 1.00 AMA PRA Category 1 Credit™.
Course opens: 
11/20/2026
Course expires: 
11/19/2028
Cost:
$0.00
Rating: 
0

Speaker:

  • Jacob Miller, MD is employed by the Cleveland Clinic Foundation.

Planners:

  • Malcolm Mattes, MD, is employed by Rutgers Cancer Institute. Dr. Mattes has research funding from Gilead Sciences [ended 8/30/2025].
  • Avinash Chaurasia, MD is employed by the U.S. Army and has no relevant financial relationships to disclose.

Reviewer:

  • Michael Haddock, MD is employed by Mayo Clinic and has no relevant financial relationships to disclose.

All relevant financial relationships have been mitigated.

The American Society for Radiation Oncology (ASTRO) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Available Credit

  • 1.00 AMA PRA Category 1 Credit™

    The American Society for Radiation Oncology (ASTRO) is accredited by the Accreditation Council for Continuing Medical Education for physicians. ASTRO designates this for a maximum of 1.00 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

  • 1.00 Certificate of Attendance
    This activity was designated for 1.00 AMA PRA Category 1 Credit™.

Price

Cost:
$0.00
Please login or register to take this course.

Activity Fees

This activity is included in the ASTRO Academy Subscription. To purchase the subscription beginning December 1, 2026, please go to the ASTRO Product Catalog.

ASTRO members and Academy subscribers must log in to the ASTRO Academy to view and receive the corresponding rate:

  • Academy Subscriber: $0
  • Member: $99
  • Member-in-Training / Student Member / Postdoctoral Fellow Member: $49
  • Nonmember: $149

Discounts
Please email ASTRO eLearning to inquire about the discounts below.

  • If you are an ASTRO member residing in a low- or lower-middle-income economy country, as identified by the World Bank, you can receive a 50% discount off the activity fee.
  • If you are an ASTRO member residing in an upper-middle-income economy country, as identified by the World Bank, you can receive a 25% discount off the activity fee.

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