Management of Locally Recurrent Head and Neck Cancer

Locally recurrent HNSCC in the setting of prior radiation therapy is a challenging clinical scenario. In this activity we present two variants of locally recurrent HNSCC after prior RT and explore the use of surgery, re-irradiation and systemic therapy either alone or in combination with one another supported by available data. The activity has a moderator, one head and neck surgeon, one head and neck radiation oncologist and one head and neck medical oncologist. The head and neck radiation oncologist covers re-irradiation with the use of IMRT, SBRT and proton therapy.

Topics:

  1. Case Presentations and Current Guidelines
    Monica E. Shukla, MD
  2. Salvage Surgery in HNSCC: A Surgical and Immunological Perspective
    Joseph Zenga, MD
  3. The Role of Reirradiation for Locally Recurrent Squamous Cell Cancer of the Head & Neck 
    Linda Chen, MD
  4. The Role of Systemic Therapy for Locally Recurrent Squamous Cell Carcinoma of the Head and Neck in the Setting of Prior Radiation Therapy
    Dan P. Zandberg, MD
  5. Q and A
    Monica E. Shukla, MD - Moderator
    Full Panel

This activity is available from January 6, 2026, through 11:59 p.m. Eastern time on January 5, 2028. 

The content was originally presented and recorded at the 2025 ASTRO Annual Meeting.

Target Audience

The activity is designed to meet the interests of medical oncologists, radiation oncologists, surgeons, nurses, physicists, radiation dosimetrists and residents.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Understand how to best sequence available treatment modalities (surgery, reirradiation and systemic therapy) in locally recurrent HSCC in the setting of prior RT.
  • Understand available re-irradiation modalities and their safety and efficacy data. Understand why one would/should pick one re-irradiation modality over another.
  • Understand the role/limitations of systemic therapy and salvage surgery in the treatment of locally recurrent HNSCC in the setting of prior RT.
Course summary
Available credit: 
  • 1.00 AMA PRA Category 1 Credit™

    The American Society for Radiation Oncology (ASTRO) is accredited by the Accreditation Council for Continuing Medical Education for physicians. ASTRO designates this Enduring material for a maximum of 1.00 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

  • 1.00 Certificate of Attendance
    This activity was designated for 1.00 AMA PRA Category 1 Credit™.
Course opens: 
01/06/2026
Course expires: 
01/05/2028
Cost:
$149.00
Rating: 
0
  • Monica E. Shukla, MD, is employed by Medical College of Wisconsin and Advocate Aurora Health. 
  • Joseph Zenga, MD, is employed by Medical College of Wisconsin. 
  • Dan P. Zandberg, MD, is employed by University of Pittsburgh Medical Center/Hillman Cancer Center.  
  • Linda Chen, MD, is employed by Memorial Sloan Kettering Cancer Center and the University of Chicago. 

All relevant financial relationships have been mitigated.

The American Society for Radiation Oncology (ASTRO) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Available Credit

  • 1.00 AMA PRA Category 1 Credit™

    The American Society for Radiation Oncology (ASTRO) is accredited by the Accreditation Council for Continuing Medical Education for physicians. ASTRO designates this Enduring material for a maximum of 1.00 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

  • 1.00 Certificate of Attendance
    This activity was designated for 1.00 AMA PRA Category 1 Credit™.

Price

Cost:
$149.00
Please login or register to take this course.

Course Fees:
ASTRO members must log in to the ASTRO website to view and receive the member rate.

  • Nonmember: $149
  • Member: $99
  • Member-in-Training: $49
  • Student/Graduate Student/PGY-1 Member: $49
  • Postdoctoral Fellow Member: $49

If you are an ASTRO member from a low or lower-middle income country, as identified by the World Bank, you can receive a 50% discount off your corresponding registration for this activity. Please email [email protected] to inquire about the discount.

Policies:
No refunds, extensions, or substitutions will be made for those participants who, for any reason, have not completed the activity by the expiration date. 

Participants using ASTRO Academy activities to satisfy the requirement of a Continuing Certification (MOC) program should verify the credit number and type and availability dates of any activity before making a purchase. No refunds, extensions, or substitutions will be made for participants who have purchased activities that do not align with their MOC requirement.

The activity and its materials will only be available on the ASTRO website until January 5, 2028, regardless of purchase date. At the expiration of the activity, participants will no longer have access to the activity or its materials. ASTRO reserves the right to remove an activity before its expiration date. 

Required Hardware/software

One of the two latest versions of Google Chrome, Mozilla Firefox, Internet Explorer or Safari.